Neher and Sakmann heard single ion channels through a suction-sealed glass pipette
To read the picoampere flicker of a single ion channel, they quit amplifying harder and instead sealed glass to the membrane until the noise collapsed.
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1,000 PUBLISHED CASES · REGULARLY UPDATEDNBA elimination math: a MIP crystal ball beat official standings by 4.1 games
MIP models call NBA clinches and eliminations exactly, catching the league's own standings errors by an average of 4.1 games.
Read the caseNando's made a brand film you didn't need eyes to see
With restaurants shut, Nando's Malaysia released an 'Unwatchable' film — an immersive audio piece serving heat, flavour and vibes to the imagination.
Read the caseNando's answered Burger King's mouldy Whopper with a photo of crumbs
When Burger King let a Whopper rot to prove no preservatives, Nando's Malaysia answered on a tiny budget: its burger never moulders — it gets eaten first.
Read the caseNanchengxiang beat Beijing fast-food economics with one storefront open 6am to 10pm
Beijing’s per-square-meter king runs community stores all day on three menus, with a ¥3 self-serve breakfast that fills the dinner rush
Read the caseNaked Threat: Refuge's campaign that made threatening to share intimate images a crime
A domestic-abuse charity rebranded a legal loophole itself as the threat, and within months the UK government rewrote the law.
Read the caseMudah.my released 32665, a lucky number whose secret was the brand
Ranked 10th among Chinese Malaysians and taboo at New Year, Mudah seeded 32665 as a fortune code — then revealed the digits spelled the brand.
Read the caseMingming Henmang scaled snack discount to 30,000 stores — then hit the scale
Loose snacks priced by weight, straight from 2,500 factories, zero franchise fee — until mis-weighing scandals forced a 10x-refund trust reset
Read the caseMexico split the network from the service to break its telecom duopoly
Mexico tendered a wholesale-only LTE network whose operator may never sell to end users — any retailer can lease capacity and take on the incumbent.
Read the caseThe Met Unframed: Verizon rebuilt the closed Metropolitan Museum as a 5G virtual gallery
With New York museums restricted, Verizon and The Met opened a mobile-only 3D replica — 12 galleries, 50 masterpieces, games that unlock art.
Read the caseMayor and Queloz caught the first exoplanet in a star's 56 m/s wobble
Planet hunters were waiting decades for a Jupiter-like orbit; Geneva's rebuilt spectrograph sampled fast and found a giant on a 4.2-day lap nobody believed.
Read the caseMaxis turned rival networks' YouTube buffering into a free art gallery
Rival networks made YouTube viewers buffer. Maxis filled the wait with art — the Buffer Art Gallery turned competitors' slow speeds into the case for 4G.
Read the caseMaxis took iPhone 12 pre-orders with an ad for a phone it couldn't show
Apple's embargo barred showing the new iPhone. Maxis launched a pre-order film for an invisible 'AirPhone 12' — and owned the launch window anyway.
Read the caseMalaysia Airlines turned a historic Klang Valley water cut into a reason to fly
As odour pollution shut treatment plants and the state sent water trucks, Malaysia Airlines offered the other fix: fly to states that still have water.
Read the caseManna's COVID drone loop delivered prescriptions to locked-down Ireland in 3 minutes
Manna swapped its stalled takeaway trial for a GP-to-doorstep drone loop during lockdown — a 2 km radius at over 50 mph, under three minutes.
Read the caseLloyd's Register graded every hull so underwriters could price risk they had never seen
Coffee-house underwriters built the first ship survey and grading standard — the A1 rating made risk legible and became the world's classification model.
Read the caseLibby turned cosmic rays into a clock that dates anything ever alive
Cosmic rays lace the air with radioactive carbon-14; living things hold a fixed dose and, once dead, it ticks away — Libby made age a measurement.
Read the caseLaoxiangji announced its national expansion with a 200-yuan launch and 140M views
With no ad budget, a Chinese fast-food chairman made cheapness itself the story — a village stage and a hen under his arm produced 140 million views.
Read the caseKura Sushi turned returned plates into a prize lottery — 25 years, until staff skimmed it
Kura built Bikkurapon on a counter it already had: five returned plates buy a roulette spin, a capsule toy pays the loyalty bill, and families keep ordering.
Read the caseKoolboks stored cold as ice, then sold it at $10 a month
A camping-fridge startup pivoted to Africa's off-grid vendors: solar freezers that bank cold in water for days, paid in $10 mobile-money installments.
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